Being fed up, tried a change (5)
I believe the answer is:
tired
'being fed up' is the definition.
(thesaurus)
'tried a change' is the wordplay.
'a change' indicates an anagram.
'tried' anagrammed gives 'TIRED'.
(Other definitions for tired that I've seen before include "Are American cars so" , "Weary or fed up" , "In need of rest" , "Depleted of energy" , "Zonked" .)