Being fed up, tried to change (5)
I believe the answer is:
tired
'being fed up' is the definition.
(thesaurus)
'tried to change' is the wordplay.
'to change' is an anagram indicator.
'tried' is an anagram of 'TIRED'.
(Other definitions for tired that I've seen before include "Worn-out" , "getting bored" , "Exhausted" , "Weary, fatigued" , "Zonked" .)