Being fond of sex, say, could make nuts ache (8)
I believe the answer is:
unchaste
'being fond of sex say' is the definition.
I can't judge whether this definition defines the answer.
'make nuts ache' is the wordplay.
'make' indicates anagramming the letters.
'nuts'+'ache'='nutsache'
'nutsache' with letters rearranged gives 'UNCHASTE'.
'could' acts as a link.
Can you help me to learn more?
(Other definitions for unchaste that I've seen before include "Lascivious" , "Not decent and virtuous" , "Engaging in illicit affairs" , "Enjoying sex" , "libertine" .)