Being out of practice can make us try (5)
I believe the answer is:
rusty
'being out of practice' is the definition.
(synonyms)
'make us try' is the wordplay.
'make' indicates an anagram.
'us'+'try'='ustry'
'ustry' with letters rearranged gives 'RUSTY'.
'can' acts as a link.
(Other definitions for rusty that I've seen before include "showing sign of inactivity?" , "affected by inactivity" , "(Of iron) corroded" , "Reddish," , "Impaired through lack of use" .)