Beware that we depart, thus making you suffer (4)
I believe the answer is:
bear
'suffer' is the definition.
(I know that suffer can be written as bear)
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for bear that I've seen before include "someone being ill-mannered" , "Endure; animal" , "Give birth to - large mammal" , "Show" , "Put up with - speculator" .)