Big and regal. Confused? (5)
I believe the answer is:
large
'big' is the definition.
(synonyms)
'regal confused?' is the wordplay.
'confused?' indicates an anagram (I've seen 'confused' mean this).
'regal' is an anagram of 'LARGE'.
'and' acts as a link.
(Other definitions for large that I've seen before include "Of great size" , "Lake" , "At which criminals possibly are free" , "Gross" , "Elgar (anag)" .)