Big no-nos
I believe the answer is:
taboos
'big no-nos' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for taboos that I've seen before include "Religious or superstitious bans" , "Superstitious bans or prohibitions" , "Prejudices that prohibit the mention of something" , "Religious or superstitious prohibitons" , "No-nos" .)