Crossword Genius

Big vessel in sea or tank (5)

Ross

I believe the answer is:

aorta

'big vessel' is the definition.
(I've seen this in another clue)

'in sea or tank' is the wordplay.
'in' indicates a hidden word.
'AORTA' is hidden in the letters of 'sea or tank'.

(Other definitions for aorta that I've seen before include "vital transporter" , "This carries blood from the heart" , "One leads from heart" , "Main artery from heart" , "Trunk artery from the heart" .)

I've seen this clue in The Globe and Mail.
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