Bit of a mishap: Grand Canal emptied and burning (6)
I believe the answer is:
glitch
'bit of a mishap' is the definition.
'emptied and burning' is the wordplay.
'emptied' becomes 'gl' (I can't explain this - if you can you should believe this answer much more).
'and' is a charade indicator (letters next to each other).
'burning' becomes 'itch' (both can mean a strong desire).
'gl'+'itch'='GLITCH'
'grand canal' acts as a link.
This may not be correct. Some or all of it may belong to another bit of the clue.
(Other definitions for glitch that I've seen before include "Unexpected failure or error" , "Small fault preventing proper working" , "Technological problem" , "Fault (electronics)" , "Temporary fault" .)