Bit of a thinker devising a ploy in bed (6,4)
I believe the answer is:
pineal body
'bit of a thinker' is the definition.
(part of the brain)
'devising a ploy in bed' is the wordplay.
'devising' is an anagram indicator.
'a'+'ploy'+'in'+'bed'='aployinbed'
'aployinbed' is an anagram of 'PINEAL BODY'.
I've seen this clue in The Guardian.
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