Blame rise in disorder for melancholy (9)
I believe the answer is:
miserable
'melancholy' is the definition.
(thesaurus)
'blame rise in disorder' is the wordplay.
'in disorder' indicates an anagram.
'blame'+'rise'='blamerise'
'blamerise' anagrammed gives 'MISERABLE'.
'for' acts as a link.
(Other definitions for miserable that I've seen before include "Glum, wretched" , "sorrowful" , "Wretchedly unhappy" , "Wretched, doleful" , "Wretched, pitiful" .)