Bonkers seen with a male brothel-keeper (5)
I believe the answer is:
madam
'keeper' is the definition.
(madam is a kind of keeper)
'bonkers seen with a male' is the wordplay.
'bonkers' becomes 'mad' (I've seen this in another clue).
'seen with' means one lot of letters go next to another.
'male' becomes 'm' (common abbreviation).
'mad'+'a'+'m'='MADAM'
'brothel' acts as a link.
I am not very happy about this link. It may belong to another bit of the clue.
Can you help me to learn more?
(Other definitions for madam that I've seen before include "Stuck-up girl" , "Conceited girl (colloq.)" , "What you would call a female customer (or a spoiled girl!)" , "Courteous form of address to a woman" , "How one may address a woman" .)