Book initially ignored irrefutable data (4)
I believe the answer is:
acts
'book' is the definition.
(book of the Bible)
I cannot understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for acts that I've seen before include "Fifth book of the New Testament" , "Dramatic parts" , "individual performers in a show" , "Takes steps" , "Pieces of legislation" .)