Bother is found in small change perhaps (8)
I believe the answer is:
nuisance
'bother' is the definition.
(I know that nuisance is a type of bother)
'is found in small change perhaps' is the wordplay.
'found in' indicates putting letters inside.
'small change perhaps' becomes 'nuance' (I can't explain this - if you can you should give a lot more credence to this answer).
'is' placed within 'nuance' is 'NUISANCE'.
Can you help me to learn more?
(Other definitions for nuisance that I've seen before include "Pest, source of annoyance" , "Pest or irritation" , "troublesome type" , "Something which annoys" , "One causing annoyance" .)