Bother the worried butler about nothing (7)
I believe the answer is:
trouble
'bother' is the definition.
(synonyms)
'worried butler about nothing' is the wordplay.
'worried' is an anagram indicator (worry can mean to interfere with or disturb).
'about' is an insertion indicator.
'nothing' becomes 'O' (looks like zero - 0).
'butler' anagrammed gives 'truble'.
'truble' enclosing 'o' is 'TROUBLE'.
'the' acts as a link.
(Other definitions for trouble that I've seen before include "Difficulty, problems" , "Trial, care, worry" , "Nuisance, bother" , "Discord" , "that follow witches' toil?" .)