Bottle perhaps attached to optic? (5)
I believe the answer is:
nerve
I believe this is a double definition.
'bottle' is the first definition.
(thesaurus)
'perhaps attached to optic?' is the second definition.
(optic nerve)
(Other definitions for nerve that I've seen before include "Cool courage" , "Temerity" , "Confidence" , "Sauce" , "Courage - impertinence" .)