Brash and old, running round university (4)
I believe the answer is:
loud
'brash' is the definition.
(I've seen this before)
'old running round university' is the wordplay.
'running' indicates an anagram (the letters run around to different places).
'round' indicates putting letters inside.
'university' becomes 'U' (abbreviation as in UMass).
'old' with letters rearranged gives 'lod'.
'lod' placed around 'u' is 'LOUD'.
'and' acts as a link.
(Other definitions for loud that I've seen before include "Brash" , "Flashy" , "booming" , "At high volume" , "strongly audible" .)