Break with Virginia gets accountant into trouble (8)
I believe the answer is:
vacation
'break' is the definition.
(I've seen this before)
'virginia gets accountant into trouble' is the wordplay.
'virginia' becomes 'va' (US state abbreviation).
'gets' means one lot of letters go next to another.
'accountant' becomes 'CA' (abbreviation for chartered accountant).
'trouble' indicates anagramming the letters.
'into' with letters rearranged gives 'tion'.
'va'+'ca'+'tion'='VACATION'
'with' acts as a link.
(Other definitions for vacation that I've seen before include "Leisure time away from work" , "break" , "Leave" , "Holiday period" , "An American holiday" .)