Brief appointment — out of bed first (6)
I believe the answer is:
update
'brief' is the definition.
(I've seen this before)
'appointment out of bed first' is the wordplay.
'appointment' becomes 'date' ('date' can be a synonym of 'appointment').
'out of bed' becomes 'up' ('up' can be a synonym of 'out of bed').
'first' is a charade indicator (letters next to each other).
'date' put after 'up' is 'UPDATE'.
(Other definitions for update that I've seen before include "Bulletin" , "Brief" , "Latest news" , "change of status" , "Bring to the latest state, records say" .)