Brief paralysis of one in a game (5)
I believe the answer is:
polio
'brief paralysis' is the definition.
'polio' can be an answer for 'paralysis' (thesaurus). I'm not sure about the 'brief' bit.
'one in a game' is the wordplay.
'one' becomes 'i' (Roman numeral).
'in' means one lot of letters goes inside another.
'a game' becomes 'polo' (polo is a kind of game).
'i' put inside 'polo' is 'POLIO'.
'of' is the link.
Can you help me to learn more?
(Other definitions for polio that I've seen before include "Viral disease causing paralysis" , "Paralysing disease" , "Acute viral disease" , "rarely seen complaint" , "Viral disease which can cause paralysis ( 5)" .)