Bring in acne treatment of significance (10)
I believe the answer is:
importance
'significance' is the definition.
(I have seen 'Great significance ' mean 'importance' so perhaps 'significance' could also mean 'importance')
'bring in acne treatment' is the wordplay.
'bring in' becomes 'import' (I've seen this before**).
'treatment' indicates an anagram.
'acne' with letters rearranged gives 'ance'.
'import'+'ance'='IMPORTANCE'
'of' acts as a link.
(Other definitions for importance that I've seen before include "moment" , "The -- of Being Earnest" , "weight" , "Great significance" , "value" .)