Buffalo drive (5)
I believe the answer is:
steer
This clue is a double definition.
'buffalo' is the first definition.
(thesaurus)
'drive' is the second definition.
(thesaurus)
(Other definitions for steer that I've seen before include "Guide, control" , "Guide (eg, a ship)" , "Pilot a boat in desired direction" , "What cowboys try to do to" , "give guidance" .)