Buffalo's Great Lake (4)
I believe the answer is:
erie
'buffalo's great lake' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for erie that I've seen before include "A Great American lake - sounds spooky" , "Lake between Canada and the US" , "Spooky-sounding" , "One of the Great Lakes" , "North american lake sounds spooky" .)