Building location around starting point (6)
I believe the answer is:
palace
'building' is the definition.
(I have seen 'Large building' mean 'palace' so perhaps 'building' could also mean 'palace')
'location around starting point' is the wordplay.
'location' becomes 'place' (a location is a place).
'around' means one lot of letters goes inside another.
'starting point' becomes 'A' (as in the phrase 'get from A to B').
'place' placed around 'a' is 'PALACE'.
(Other definitions for palace that I've seen before include "Royal residence" , "See 10" , "Royal mansion" , "Locality round a monarch's official residence" , "Head of state's residence" .)