Business forfeiture by US conglomerate is a huge thing (8)
I believe the answer is:
colossus
'thing' is the definition.
(I have seen 'Great thing' mean 'colossus' so perhaps 'thing' could also mean 'colossus')
'business forfeiture by us' is the wordplay.
'business' becomes 'co' (short for company).
'forfeiture' becomes 'loss' (I've seen this before).
'by' is a charade indicator (letters next to each other).
'co'+'loss'+'us'='COLOSSUS'
'conglomerate is a huge' is the link.
This may not be right. Some or all of it may be part of another bit of the clue.
Can you help me to learn more?
(Other definitions for colossus that I've seen before include "An immense state as once at Rhodes (8)" , "Huge statue" , "Abnormally powerful person" , "Enormous statue" , "VIP" .)