Business removes knots for districts (8)
I believe the answer is:
counties
'districts' is the definition.
(county is a kind of district)
'business removes knots' is the wordplay.
'business' becomes 'co' (short for company).
'removes knots' becomes 'unties' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'co'+'unties'='COUNTIES'
'for' acts as a link.
Can you help me to learn more?
(Other definitions for counties that I've seen before include "Administrative divisions" , "administrative areas" .)