Business will always be important (6)
I believe the answer is:
matter
'be important' is the definition.
(I've seen this before)
I don't understand how the rest of the clue works.
Can you help me to learn more?
(Other definitions for matter that I've seen before include "Physical substance" , "Affair; be important" , "Substance as opposed to spirit" , "Stuff - mean something" , "Substance; be important" .)