Crossword Genius

Cactus used to make mescal (6)

Ross

I believe the answer is:

peyote

(Other definitions for peyote that I've seen before include "Mescal, a cactus" , "Hallucinogenic drug from Mexican cactus" , "Hallucinogenic cactus; eye pot (anag.)" , "Cactus hallucinogen" .)

I've seen this clue in the Sydney Morning Herald.
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