Caller troubled guards in charge of minister (8)
I believe the answer is:
clerical
'minister' is the definition.
(thesaurus)
'caller troubled guards in charge' is the wordplay.
'troubled' indicates an anagram.
'guards' indicates putting letters inside.
'in charge' becomes 'ic'.
'caller' is an anagram of 'cleral'.
'cleral' enclosing 'ic' is 'CLERICAL'.
'of' is the link.
(Other definitions for clerical that I've seen before include "Relating to the clergy" , "Relating to ordained church members" , "Call Eric, being of the priesthood" , "Relating to the priesthood or office work" , "Connected with office work" .)