Calms (6)
'calms' is the definition.
(I know this)
This is all the clue.
(Other definitions for sedates that I've seen before include "Anaesthetises" , "Calms" , "keeps quiet" , "Treats with soothing or sleeping drugs" .)
(Other definitions for settles that I've seen before include "Resolves" , "Comes to rest" , "Becomes established in a place" , "seating" , "Pays the bill" .)
(Another definition for soothes that I've seen is " 'Allays, comforts, calms (7)'".)
'calms' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for allays that I've seen before include "Calms" , "Puts at rest, say fears" , "Assuages, eases" , "Diminishes or puts at rest" , "Soothes, eases" .)