Cancel out Tyneside scandal? (6)
I believe the answer is:
negate
'cancel out' is the definition.
(I've seen this in another clue)
'tyneside scandal?' is the wordplay.
'tyneside' becomes 'NE' (region in North East of England).
'scandal?' becomes 'gate' (as in Watergate and other formations).
'ne'+'gate'='NEGATE'
(Other definitions for negate that I've seen before include "Deny the truth of" , "Age ten (anag)" , "disallow!" , "Countermand" , "Make invalid" .)