Canine woe (5)
I believe the answer is:
mange
'canine woe' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for mange that I've seen before include "Disease affecting dog hair" , "Skin disease of cats and dogs" , "Parasitic skin disease" , "Domestic animals may find it very irritating" , "may have to deal with this" .)