Cannabis with change of direction makes crystal, perhaps (5)
I believe the answer is:
glass
'crystal perhaps' is the definition.
(crystal is a kind of glass)
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for glass that I've seen before include "barometer" , "Container for drinking from" , "Drink container" , "Something to drink from" , "Goblet" .)