Carl's wife in "Up" (5)
I believe the answer is:
ellie
'carl's wife in up' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for ellie that I've seen before include "a wake-up call" , "woman" , "Name of girl in The Water Babies (Kingsley)" , "Diminutive girl" , "Little Eleanor" .)