Cars peculiar to USA (5)
I believe the answer is:
autos
'cars' is the definition.
('auto' can be a synonym of 'car')
'peculiar to usa' is the wordplay.
'peculiar' indicates anagramming the letters (a peculiar or strange ordering of the letters).
'to'+'usa'='tousa'
'tousa' with letters rearranged gives 'AUTOS'.
(Other definitions for autos that I've seen before include "Freeway traffic" , "Religious dramas" , "Cars" .)