Case confined to research establishment (5)
I believe the answer is:
chest
'case' is the definition.
(both are types of container)
'confined to research establishment' is the wordplay.
'confined to' indicates a hidden word (the answer is confined in the clue).
'CHEST' is hidden in the letters of 'research establishment'.
(Other definitions for chest that I've seen before include "Breast - case" , "drawers in it!" , "Box - breast" , "Rib area" , "It's enclosed by the ribs" .)