Case of chronically having stone in bladder? (4)
I believe the answer is:
cyst
'bladder?' is the definition.
(I've seen this before)
'case of chronically having stone' is the wordplay.
'case of' says to hollow out the word (remove centre letters) (outsides of).
'having' is a charade indicator (letters next to each other).
'stone' becomes 'st'.
'chronically' with its centre taken out is 'cy'.
'cy'+'st'='CYST'
'in' is the link.
(Other definitions for cyst that I've seen before include "Thin-walled cavity containing liquid" , "Bladder" , "Abnormal body cavity" , "Accumulation of matter" , "Small growth" .)