Case of gangrene found by lady who cleans ward (6)
I believe the answer is:
charge
'ward' is the definition.
(thesaurus)
'case of gangrene found by lady who cleans' is the wordplay.
'case of' says to hollow out the word (remove centre letters) (outsides of).
'found by' means one lot of letters go next to another.
'lady who cleans' becomes 'char'.
'gangrene' with its middle taken out is 'ge'.
'ge' put after 'char' is 'CHARGE'.
(Other definitions for charge that I've seen before include "Offensive - fee" , "Rush to exact payment?" , "Formally accuse (someone)" , "Accuse or rush forward" , "Price asked; fill" .)