Case of Marianne disrupting class, abandoning school - some spirit! (6)
I believe the answer is:
mescal
'some spirit' is the definition.
(mescal is an alcoholic drink)
I cannot understand how the remainder of the clue works.
(Other definitions for mescal that I've seen before include "Intoxicant from agave" , "Drink distilled from agave" , "Colourless Mexican spirit made from plant sap" .)