Catch a misfit (1,4,3,2,5)
I believe the answer is:
a fish out of water
'catch' is the definition.
(I've seen this before)
'a misfit' is the wordplay.
'misfit' becomes 'fish out of water' (I've seen this in another clue).
'a'+'fishoutofwater'='A FISH OUT OF WATER'
(Other definitions for a fish out of water that I've seen before include "one unsuited to situation" , "one feeling out of place" , "Catch" .)