Catholic in the Italian uprising, supported by state, reaches objective (8)
I believe the answer is:
clinical
'objective' is the definition.
('clinical' can be similar in meaning to 'objective')
'catholic in the italian uprising supported by state' is the wordplay.
'catholic' becomes 'c' (abbreviation as in RC for Roman Catholic).
'the italian' becomes 'il' (the in Italian).
'uprising' is a reversal indicator.
'supported by' means one lot of letters go next to another (letters go below - in down clue).
'state' becomes 'cal' (I've seen this in other clues**).
'in'+'il'='inil'
'inil' reversed gives 'lini'.
'c'+'lini'+'cal'='CLINICAL'
'reaches' is the link.
(Other definitions for clinical that I've seen before include "Based on observed signs or symptoms" , "Hospital-like - strictly objective" , "description of a form of medicine" , "Cool and detached, or based on observed symptoms" , "cold?" .)