Catty remark from Ms Farrow? It hurts! (5)
I believe the answer is:
miaow
'catty remark' is the definition.
(I know that house cat produced sound miaow)
'ms farrow? it hurts' is the wordplay.
'ms farrow?' becomes 'Mia' (actress Mia Farrow).
'it hurts' becomes 'ow' (exclamation of pain).
'mia'+'ow'='MIAOW'
'from' acts as a link.
(Other definitions for miaow that I've seen before include "Cat chat?" , "as the Queen perhaps goes" , "Sound from a tabby?" , "Kitty's going" , "What the cat says" .)