Cause to lose hope (10)
I believe the answer is:
dishearten
(Other definitions for dishearten that I've seen before include "Cause (someone) to lose confidence" , "cast down" , "Bring down" , "dismay?" , "Take away bottle" .)
I believe the answer is:
dishearten
(Other definitions for dishearten that I've seen before include "Cause (someone) to lose confidence" , "cast down" , "Bring down" , "dismay?" , "Take away bottle" .)