Celebrity against second sequel to go on a hunger strike (6)
I believe the answer is:
starve
'go on a hunger strike' is the definition.
(I've seen this in another clue)
'celebrity against second sequel' is the wordplay.
'celebrity' becomes 'star' (a star is a celebrity or famous person).
'against' becomes 'v' (versus).
'second sequel' becomes 'e' (2nd letter of 'sequel').
'star'+'v'+'e'='STARVE'
'to' acts as a link.
(Other definitions for starve that I've seen before include "Stop feeding" , "Suffer great hunger" , "Vaster (anag)" , "Suffer from lack of food" , "Suffer extreme hunger" .)