Cellulose nitrate explosive, George! Count out huge weight! (9)
I believe the answer is:
guncotton
'cellulose nitrate' is the definition.
(I know that cellulose nitrate can be written as guncotton)
'explosive george count out huge weight' is the wordplay.
'explosive' is an anagram indicator.
'george' becomes 'g'.
'out huge weight' becomes 'ton' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'g'+'count'='gcount'
'gcount' anagrammed gives 'guncot'.
'guncot'+'ton'='GUNCOTTON'
Can you help me to learn more?
(Another definition for guncotton that I've seen is " Type of explosive".)