Centre visited by male on opium? (4)
I believe the answer is:
numb
'centre visited by male on opium?' is the definition.
I can't judge whether this defines the answer.
'centre visited by male' is the wordplay.
'centre' becomes 'nub' (both can mean the core or essence of an issue).
'visited by' is an insertion indicator.
'male' becomes 'm' (common abbreviation).
'nub' placed around 'm' is 'NUMB'.
Can you help me to learn more?
(Other definitions for numb that I've seen before include "Lacking sensation" , "Feeling nothing" , "Stunned, insensible" , "Without feeling" , "Deprived of sensation" .)