Certainly not the best of spirits! (5)
I believe the answer is:
ghoul
'best of spirits' is the definition.
The answer and definition can be both people as well as being singular nouns.
Perhaps you can see an association between them that I don't see?
I don't understand how the rest of the clue works.
Can you help me to learn more?
(Other definitions for ghoul that I've seen before include "shade" , "Morbid voyeur" , "Morbid type" , "Macabre fiend" , "Evil presence" .)