Certainly using every available method (2,3,5)
I believe the answer is:
by all means
'certainly' is the definition.
(I've seen this in another clue)
'using every available method' is the wordplay.
'using' becomes 'by' (I've seen this in other clues).
'every' becomes 'all' (similar in meaning).
'available method' becomes 'means' (I've seen this in another clue. I am not sure about the 'available' bit.).
'by'+'all'+'means'='BY ALL MEANS'
Can you help me to learn more?
(Other definitions for by all means that I've seen before include "Please do" , "expression of agreement" , "Of course, certainly" , "using every possible method" , "how the versatile work?" .)