Chance of work having left college totally discontented (11)
I believe the answer is:
opportunity
'chance of work' is the definition.
'opportunity' can be an answer for 'chance' (synonyms). I am not certain of the 'of work' bit.
'having left college totally discontented' is the wordplay.
'having' becomes 'troppo' (I am not sure about this - if you are sure you should believe this answer much more).
'left' says the letters should be written in reverse.
'college' becomes 'uni' (short for university).
'discontented' means to remove the middle letters (the word's contents are removed).
'totally' with its middle taken out is 'ty'.
'troppo' written backwards gives 'opport'.
'opport'+'uni'+'ty'='OPPORTUNITY'
Can you help me to learn more?
(Other definitions for opportunity that I've seen before include "One may knock" , "Break" , "Crack of the whip" , "window" , "Chance" .)