Change result by replacing novice finally with adult (6)
I believe the answer is:
affect
'change' is the definition.
(affecting is a kind of changing)
I cannot understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for affect that I've seen before include "Act upon" , "front" , "impress" , "Have impact on or arouse sadness in" , "Pretend - to have influence on events" .)